Advertise on the STP website to reach your target audience effectively and economically!
Location: Maryland Heights, MO
Job Title: Senior/Principal Pathologist
Inotiv is a consultant-based, contract research lab that provides integrated services for discovery and preclinical drug development. Inotiv offers a unique alternative by integrating nonclinical disciplines in pharmacology, drug metabolism and pharmacokinetics, toxicology, and pathology in order to provide robust nonclinical evaluations of drug efficacy, safety, systemic exposure, and metabolism.
We are currently looking for a Senior/Principal Pathologist experienced with toxicology and drug development and with a passion for science and quality. Pathologists at Inotiv serve as technical experts and consultants in pathology and related fields. We work in a collaborative environment on projects throughout the discovery and development continuum. The ideal candidate will have a broad knowledge of toxicological pathology across multiple species as well as an in depth knowledge in a specialty area or organ system.
- Interpret and report pathology findings in exploratory and regulatory studies including correlating microscopic findings to macroscopic observations, organ weight changes, and clinical pathology data
- Conduct pathology peer reviews
- Evaluate efficacy studies or animal models of disease
- Maintain a current knowledge of pathology literature, best practices, and industry directions
Additional responsibilities may include:
- Providing pathology expertise for regulatory submissions and regulatory responses
- Mentoring and providing senior-level guidance to less experienced pathologists
- Consulting in toxicology and/or pathology
- Demonstrating scientific leadership through participation in professional organizations, presentations, and publications
- DVM and Diplomate of ACVP (anatomic pathology) or equivalent qualification
- Industrial experience (3+ years)
- Experience interpreting and reporting pathology findings for regulated (GLP) studies, preferably in a pharmaceutical or biotechnology company or a CRO conducting studies for pharmaceutical or biotechnology companies
- Strong, effective written and oral communication skills including the ability to organize and clearly present complex data and concepts
- Ability to work in a fast-paced environment, manage multiple projects, demonstrate consistent productivity, and meet project timelines
- Ability to work independently and collaboratively
- Remote location (work from home office) is possible
Salary and Benefits:
Inotiv offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
Company: Vertex Pharmaceuticals
Location: Boston, MA
Job Title: Senior Pathologist
Preclinical Safety Assessment (PSA) is a global function responsible for the design and conduct of comprehensive nonclinical safety programs for the evaluation of Vertex therapies at all stages of discovery and development. Vertex Pharmaceuticals uses cutting edge science and technology to perform robust assessments of novel therapies for the treatment of the most serious diseases with unmet medical need. Our culture enables individual empowerment where "We Wins", "Fearless Pursuit of Excellence", and "Innovation" are more than just corporate values; they are part of our everyday lives. PSA pathologists have significant roles in the drug development process beginning in early discovery and continuing through the entire drug development value chain resulting in successful registration and marketing approval.
- Anatomic pathology evaluation of nonGLP and GLP Toxicity studies from lead identification/optimization stage through registration and post-marketing in collaboration with other veterinary anatomic and clinical pathologists
- Peer review of nonGLP and GLP toxicology studies including carcinogenicity studies
- Scientific leadership in the design, conduct and interpretation of pathology endpoints for animal model development, target identification/validation, and in vivo pharmacology and nonclinical biomarker development studies
- Anatomic pathology evaluation of Translational Biology in vivo efficacy studies and animal model development including the use of molecular diagnostic and digital imaging technologies
- Interpretation and communication of findings to cross-functional project teams and senior management
- Collaboration with PSA, Discovery and Biomarker scientists to identify translational safety biomarkers for possible use in clinical studies
- Participation in regulatory submission document preparation, poster presentations and scientific publications, including addressing queries from global health authorities
- The position includes opportunities for potential additional roles including:
- Preclinical safety representative on discovery and/or development project teams
- Nonclinical safety evaluation of in-licensing opportunities supporting business development
- DVM or equivalent and ACVP/ECVP board certification in veterinary anatomic pathology
- PhD in a relevant scientific discipline is strongly preferred
- 10 years of work experience in Discovery and/or Toxicologic pathology in the pharmaceutical/biotechnology sector including the conduct of GLP peer reviews
- Work experience as a project team representative in the pharmaceutical/biotechnology sector is desirable
- Demonstrated excellence in oral and written communication skills, including authorship of regulated pathology reports
- Work experience in issue resolution, scientific collaboration, guidance and mentoring of junior pathologists
Company: Charles River Laboratories
Location: Laval (greater Montreal area), Canada
Job Title: Senior or Principal Veterinary Pathologist
For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
We are seeking an experienced Senior or Principal Veterinary Pathologist for the group of Pathology, located in Senneville or Laval (greater Montreal area) in Canada. The new Veterinary Pathologist will provide scientific expertise in pathology according to sponsors’ requirements and scientific and technical expertise in immunohistochemistry techniques and associated molecular pathology application, as required. Additionally, this role may assist with necropsy supervision and will perform histopathological examinations on a wide variety of laboratory species. Writing comprehensive pathology reports in support of the toxicology program will also be part of the responsibilities, as will conducting peer reviews in pathology and may review clinical pathology data. Provide advanced scientific expertise for experimental design and other aspects of research studies as needed. Act as coordinator pathologist for important sponsors. Provide training, technical guidance and mentorship to laboratory staff and to less experienced pathologists.
The following are minimum requirements:
- Doctorate in Veterinary Medicine or equivalent, and formal Residency training in Veterinary Pathology;
- Board certification by the American College of Veterinary Pathologists (ACVP) or European College of Veterinary Pathologists (ECVP);
- 5 to 10 years of relevant experience in toxicologic or investigative pathology in a CRO, pharmaceutical or biotechnology industry;
- Fluent in spoken and written English required, French would be an asset;
- Management skills and mentoring experiences would be an asset;
- Strong knowledge of related legislation, principles, practices and procedures;
- High degree of self-motivation with effective organizational and time management skills;
- Collaborative and team building skills.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many people across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.
For more information, please visit www.criver.com
Should you have any questions or would like to get more information on the Senior Veterinary Pathologist role, please contact one of the Senior Directors of the Pathology service:
Location: Somerset, NJ
Job Title: Veterinary Anatomic Pathologist
Come join a global team of veterinary pathologists focused on providing high quality support to nonclinical studies spanning all phases of drug development. Due to our continuous growth, we have a great opportunity for a Veterinary Anatomic Pathologist to join our team at our site in Somerset, NJ. Covance’s work in developing new pharmaceutical solutions has an incredible impact on millions of lives worldwide. Be a part of this life-saving work!
Duties and responsibilities may include:
- Perform the complex microscopic evaluation and interpretation of tissue sections from animals exposed to test materials and correlate these findings with necropsy, organ weight and clinical pathology findings.
- Author comprehensive pathology narrative reports of microscopic, gross, and clinical pathology findings, while meeting report deadlines.
- Provide pathology support in the interpretation of chemical or drug-related toxicology findings in safety studies.
- Supervise necropsies and provide scientific guidance to necropsy technicians to ensure accuracy and compliance with protocols and SOP’s.
- Communicate the significance of pathologic findings to study directors, clients and other individuals.
- Serve as core pathologist for key client requesting this service.
- Alternatively, exhibit skills in specialty areas such a neuropathology, ocular pathology, immunohistochemistry, etc. and be responsible for evaluating specialty toxicology studies or specialty portions of studies.
What we’re looking for in you:
- DVM/VMD degree or equivalent.
- Formal pathology residency or graduate studies (i.e. MS, PhD) at an institution in which the training of veterinary pathologists is a primary function.
- Board certified by the American College of Veterinary Pathologists/European College of Veterinary Pathologists.
- A desire for continuous learning! Toxicologic pathology is an excited field where new discoveries are made each day! While experience in toxicologic pathology is desired, our global team has a great training program for newly boarded pathologists to launch their career in toxicologic pathology!
There is no better time to join us!
Company: Bristol-Myers Squibb
Location: New Brunswick, NJ
Job Title: Principal Veterinary Clinical Pathologist
Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.
Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.
Experienced Drug Safety Clinical Pathologist:
Bristol-Myers Squibb (BMS) is looking for an experienced clinical pathologist with the knowledge and skills to interpret and report on clinical pathology data from regulatory toxicology studies, provide scientific management for the clinical pathology laboratory, be a leader in bringing new biomarker assays into the organization and in providing clinical pathology expertise to project teams and investigative response teams.
This is an opportunity to join an expanding company and contribute meaningfully as a team member to drug development and research in a large biopharma. In addition to interpretation and assessment of material from toxicology studies, additional opportunities for this role include membership of Investigative Response Teams (IRT’s), Biomarker development, and close interaction and collaboration with Immuno-toxicology and Discovery scientists. Collaboration with our Discovery clinical pathologist is encouraged.
Important Job Responsibilities:
- Scientific management of the Clinical Pathology group in New Brunswick, NJ (1 supervisor and 4 medical technologists).
- Ensure compliance with Good Laboratory Practice and Standard Operating Procedures.
- Interpret and investigate the significance of results of clinical pathology data from toxicology studies.
- Generates clinical pathology reports that accurately and completely reflect the data collected and the significance of the data to drug registration and safety.
- Continuously evaluate and apply, where appropriate, new scientific methodology in order to maintain scientific excellence, to meet research and drug-registration needs, and to resolve toxicity-based issues.
- External contributions via presentations at scientific meetings, active membership of professional bodies and publication in peer-reviewed scientific journals are encouraged.
- Advanced degree (DVM, or equivalent), with knowledge of clinical pathology, toxicology and related disciplines (e.g., metabolism and pharmacokinetics).
- Board certification in clinical pathology (ACVP or equivalent) preferred.
- Preferably 5 years or more experience of clinical pathology in industry and/or academia.
- Effective written and oral communication, especially as they pertain to writing clear, accurate and concise reports for regulatory dossiers and submissions.
- Ability to interpret and apply available data to assess relative risk or hazard to humans.
- Knowledge of Standard Operating Procedures, Good Laboratory Practice Procedures, US and worldwide regulatory requirements and the drug development process.
Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.
Company: WuXi AppTec
Location: Minneapolis / St. Paul, MN
Job Title: Veterinary Pathologist
WuXi AppTec Pathologists contribute to a wide range of critical activities within Biocompatibility, Safety, and Toxicology Testing including but not limited to study evaluation for safety, toxicology, biocompatibility, and combined biocompatibility / toxicology studies for the medical device industry and pharmacology industries.
Reads and analyzes slides.
Provides data to Study Directors for client reports.
Provides support and subject expertise to the necropsy and histology staff.
Writes pathology reports.
Provide consultation to Study Directors on studies.
Communicate with sponsors to answer questions and discuss results regarding the pathology report.
Assistant facility veterinarian.
Evaluate pathology slides microscopically from animals that were found dead or euthanized due to morbidity to try to determine the cause of death or illness.
Communicate findings of early animal deaths to the In-Life staff and Facility Veterinarian.
Develop continuing education seminars for the staff.
Assist in bringing new technology to the pathology department.
Ability to work in a team environment and independently, as required.
Contributes to the overall operations and to the achievement of departmental goals.
Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.
Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices.
Other duties as assigned.
May be required to assist in other departments.
Experience / Education:
- DVM (Doctor of Veterinary Medicine) or equivalent.
- ACVP or ECVP Board eligibility or ACVP or ECVP Board Certification.
- State Veterinary License (State of Minnesota or other State).
- Completion of Veterinary Anatomic Pathology Residency Program.
- Experience in toxicological pathology, implant pathology and biocompatibility testing and knowledge of regulatory requirements is desirable.
- Minimum 1 year of post residency preferred.
Knowledge / Skills / Abilities:
- Proficient in Oral & Written communication skills.
- Proficient in Microsoft (Excel, Word, Outlook).
- Need to be able to read, write and understand English.
- Adaptability, flexibility and ability to manage changing priorities.
- Self-responsibility and independence, while at the same time being a team player.
Location: Columbus, OH
Job Title: Veterinary Clinical Pathologist
The successful candidate will provide: clinical pathology interpretation of results, oversight of clinical pathology laboratories, and responsible for ensuring continued regulatory compliance and validation of clinical pathology instrumentation in an evolving clinical pathology department. The department has primary focus in the evaluation and reporting of clinical pathology data generated from a variety of standard and non-standard laboratory species from non-clinical safety/efficacy studies.
- Doctor of Veterinary Medicine (DVM).
- Board Eligible under the ACVP board certification in clinical pathology.
- Experienced in interpretation of hematologic, biochemistry, cytology, urine and coagulation data in laboratory animals (e.g. rodents, dogs, NHP) and experienced with specimen evaluation from bone marrow, secretions, bodily fluids, urine sediment, bronchoalveolar lavage, cavity effusions, and FNA.
- Excellent knowledge in the principles of pathophysiology and disease and able to produce Contributing Scientist Reports.
- Individual must be able to perform research with minimum of direction and is responsible for completing projects within time and budget constraints.
- Collaboration with discovery and regulatory scientists and benchmarking/implementing state of the art clinical pathology technologies.
- Must be a US Citizen with the ability to obtain and maintain a government security clearance/DoD.
- Must be willing to work in a biosafety level 2 (BSL2) and/or 3 (BSL3) environment and able to wear appropriate respiratory protection.
- Must be willing to be immunized with licensed and FDA approved vaccines and medications recommended for persons at risk to occupational exposure of biological agents.
- Must be willing to participate in periodic drug screening.
Additional requirements may be requested at a future date:
- Ability to obtain/maintain enrollment in applicable personnel reliability programs. Enrollment requires the ability to pass commercial and/or federal background investigations.
- Ability to obtain/maintain DoJ Security Risk Assessment (SRA) approval.
- Ability to obtain/maintain CDC Select Agent Program approval.
The Following Is Desired:
- Current DACVP board certification.
- Experience (clinical and/or anatomic pathology) with the national Toxicology Program (NTP) is a plus.
- DVM plus PhD preferred.
Location: Columbus, OH
Job Title: Pathology, Director
The Pathology Manager is responsible for safe operations within the anatomic and clinical pathology laboratory sections and has overall responsibility, authority, and accountability for the management of technical lab sections (necropsy, histology, histopathology, and clinical pathology). The individual will serve as a leader in the toxicology organization and oversee 40–100 staff ranging from technicians to board certified veterinary pathologists and supervisors who support three separate sites within Battelle, as well as interact with principal investigators, program managers, members of project teams and other departments. The Pathology Manager will manage activities of the laboratory to include administrative tasks, meeting financial objectives, meeting study milestones, and training, coordinating activities between the laboratory and other groups within and external to the pathology department.
- Serves as a strategic advisor to senior level management.
- Creates and develops networks with key decision makers, current clients and potential clients.
- Serves as organization spokesperson on advanced projects and/or programs.
- Ensures Battelle’s staff, facilities, and capabilities are commiserate with the scientific, regulatory, and quality requirements of clients.
- Develops and implements strategic, operational and scientific plans.
- Defines new business areas of scientific development and contributes to the business decisions to grow Battelle’s overall capabilities.
- Performs costing for anatomic and clinical pathology tasks, monitoring financial status reports, documenting and off-normal events and scope variations.
- Ensures necropsy, histology and histopathology processes are completed in compliance with GLP’s, and SOP’s.
- Assigns staff workload and project assignments to ensure appropriate levels and skills are available to meet deadlines and client needs.
- Manages human resource activities including recruiting and hiring, performance management, and coaching opportunities for career development.
- Manages non-staff resources, including laboratories, instruments, procedures, and equipment.
- Submits capital equipment requests, required documentation for procurement, reviews bids, selects best bid based on technical evaluation and value.
- Implements, executes and communicates the policies and strategic direction of senior leadership.
- Reviews and responds to audits from internal and external clients.
- Reviews and approves proposals, reports, plans, and papers that go outside the Group.
- Performs routine safety walk-through observations and provides necessary equipment to for staff to do their job safely.
The Following Is Required:
- A DVM degree and over 5 years’ applicable experience working in anatomic pathology in a CRO including team lead/supervisory experience.
- Directly relevant experience with anatomic and clinical pathology tasks and their execution in a CRO, Pharmaceutical or Government setting.
- Consistent record of impactful performance and documented accomplishments in advancing pathology and image analysis, impacting business and operational processes, and personnel management.
- Demonstrated communication skills to effectively interact with top management internally and with client organizations, subcontractors, consultants, staff and across multiple departments (i.e. Toxicology, Pharmacology, Inhalation).
- Ability to work in a matrix organization across multiple departments (i.e. Safety Assessment, Inhalation, and Laboratory Animal Resources)
- Strong knowledge and understanding of US FDA, US EPA, and OECD Good Laboratory Practice regulations.
- customer service focus and history of successful client interactions.
The Following Is Desired:
- ACVP (American College of Veterinary Pathologists) Board certified
- 5+ Years Management experience.