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F. Hoffmann-La Roche AG, Basel, Switzerland—Roche Postdoc Fellowship (RPF) in Computational Pathology (24 months)

Company:F. Hoffmann-La Roche AG
Location:Basel, Switzerland
Job Title:Roche Postdoc Fellowship (RPF) in Computational Pathology (24 months)

Please visit the link to apply online.

At Roche, 80,000 people across 150 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity, and on seeing each other’s differences as an advantage. To innovate healthcare, Roche has ambitious plans to keep learning and growing – and is seeking people who have the same goals for themselves.

At Roche, we believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are fearless in both decision and action. And we believe that good business means a better world.

That is why we come to work every single day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The Position:

As a Postdoctoral Fellow in the Department of Global Pathology, Pharmaceutical Sciences, you will focus on a research project on digital and computational pathology with a focus on toxicologic pathology. Technologies and workflows for digital pathology will be assessed, with the goal of implementing digital slide evaluation of toxicology studies, with integration of digital slide review into an end-to-end digital lab workflow including scanning, slide sharing, annotation and machine learning/image analysis.

The Freie Universität Berlin, Fachbereich Veterinärmedizin, Institut für Tierpathologie is Roche’s academic partner for this Postdoctoral Fellowship. The partnership with academia is an important aspect of our approach.

In this position you will:

  • Compare efficiency and precision of digital vs. glass slide review
  • Implement a high throughput digital slide review workflow, with focus on developing best practices
  • Investigate possibilities for machine learning as a complement to pathologist slide evaluation
  • Work in a multidisciplinary team of veterinary pathologists, biologists and imaging specialists

This position is sponsored by the Roche Postdoctoral Fellowship Program and is initially set for two years, extension for a third year is possible. You will be based in Basel, with stays at our academic partner in Berlin.

You are a veterinarian with a postgraduate scientific degree in the field of pathology (PhD or with subsequent postdoctoral experience) and hold an international postgraduate qualification in pathology (DiplECVP, DiplACVP), or are eligible to sit the relevant exams.

You also have experience and expertise in the following:

  • Digital Pathology/Image Analysis
  • Toxicologic pathology experience is a benefit
  • Proficiency in written and spoken English

You have very good interpersonal and communication skills, are able to build good working relationships, and are an outstanding teammate. Your experience and investigative attitude allow you to work independently, to design, perform, and interpret experiments, and to embark on new scientific methodologies.

When does it start?
The start date of this fellowship is 1st November, or on availability. Please clearly indicate your preferred starting date on your motivation letter.
All applications always need to include a CV, motivation letter, a publication list and a certificate of your veterinary degree, and, if available, your PhD.

Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on


Roche is an equal opportunity employer.

National Cancer Institute, Bethesda, Maryland—Staff Scientist, Investigative Veterinary Pathologist

Company: National Cancer Institute
Location: Bethesda, Maryland
Job Title: Staff Scientist – Investigative Veterinary Pathologist


The National Cancer Institute Center for Cancer Research has an opening for a veterinary pathologist in the Molecular Pathology Unit, Laboratory of Cancer Biology and Genetics. This career position within the National Cancer Institute Intramural Research Program combines many exciting aspects of an academic appointment, with its focus on research, training and education, within the resource intensive environment of the nation’s medical research agency.

The Staff Scientist will have responsibilities for (including but not limited to):

  • Conduct research investigations and animal model validation;
  • Develop and apply capabilities in molecular diagnostics and digital pathology;
  • Educational responsibilities in training veterinary pathologists and others as comparative biomedical scientists.

Educational responsibilities:

  • Assist in the administration of a PhD-granting Comparative Biomedical Scientist Training Program (CBSTP), an NCI-administered NIH Graduate Partnership Program;
  • Recruit, train, and mentor trainees for CBSTP graduate PhD as well as veterinary student summer internships;
  • Mentor veterinarians for pathology board certification.


The successful candidate must have a D.V.M. degree or US equivalent, formal mentored postdoctoral/graduate training in pathology and research, experience with training responsibilities, and evidence of scientific research productivity sufficient to carry out the duties and responsibilities. Candidates with a Ph.D. degree, nationally/internationally recognized board certification in veterinary pathology, and experience as an employed pathologist with evidence of leadership and mentorship abilities are preferred. National pathology board certification would be required within a maximum of two years from entry on to duty, if not already held. Exceptional interpersonal, written and verbal communication skills and an ability to work cohesively in a team environment are essential.

Additional information:

Additional information about the CBSTP and the Molecular Pathology Unit is available at

The staff scientist will possess and continually enhance their professional capabilities and reputation commensurate with those of modern pathologists. The position does not include required diagnostic service pathology responsibility, although opportunity for diagnostic pathology case exposure exists.

How to apply:

Employment is through an NIH Title 42 appointment mechanism with complete constellation of full-time federal employee benefits, including relocation. Compensation commensurate with experience. Review of applications will begin December 4, 2019 and will continue until a suitable candidate is identified. Direct inquiries to Mark Simpson, D.V.M., Ph.D., Diplomate, ACVP, c/o Yvonne Jackson, Program Analyst, by email or by telephone at (240) 760-6840. Applicants should submit a curriculum vitae, bibliography, statement including relevant background, experience and motivation for seeking the position, and provide complete names and contact information for a minimum of 3 professional references, c/o Ms. Yvonne Jackson, Program Analyst, NIH building 37, room 2007, 9000 Rockville Pike, National Cancer Institute, Bethesda MD 20892;

DHHS, NIH, and NCI are equal opportunity employers

Seventh Wave Laboratories, LLC - BASi, Maryland Heights, MO—Senior Pathologist

Company: Seventh Wave Laboratories, LLC - BASi
Location: Maryland Heights, MO
Job Title: Senior Pathologist

Seventh Wave is a consultant-based, contract research lab that provides integrated services for discovery and preclinical drug development. Seventh Wave offers a unique alternative by integrating nonclinical disciplines in pharmacology, drug metabolism and pharmacokinetics, toxicology, and pathology in order to provide robust nonclinical evaluations of drug efficacy, safety, systemic exposure, and metabolism.

We are currently looking for a Senior/Principal Pathologist experienced with toxicology and drug development and with a passion for science and quality. Pathologists at Seventh Wave serve as technical experts and consultants in pathology and related fields. We work in a collaborative environment on projects throughout the discovery and development continuum. The ideal candidate will have a broad knowledge of toxicological pathology across multiple species as well as an in-depth knowledge in a specialty area or organ system. 

Key Responsibilities:

  • Interpret and report pathology findings in exploratory and regulatory studies including correlating microscopic findings to macroscopic observations, organ weight changes, and clinical pathology data 
  • Conduct pathology peer reviews
  • Evaluate efficacy studies or animal models of disease
  • Maintain a current knowledge of pathology literature, best practices, and industry directions

Additional Responsibilities may include:

  • Providing pathology expertise for regulatory submissions and regulatory responses
  • Mentoring and providing senior-level guidance to less experienced pathologists
  • Consulting in toxicology and/or pathology
  • Demonstrating scientific leadership through participation in professional organizations, presentations, and publications


  • DVM and Diplomate of ACVP (anatomic pathology) or equivalent qualification
  • Industrial experience (3+ years)
  • Experience interpreting and reporting pathology findings for regulated (GLP) studies, preferably in a pharmaceutical or biotechnology company or a CRO conducting studies for pharmaceutical or biotechnology companies
  • Strong, effective written and oral communication skills including the ability to organize and clearly present complex data and concepts
  • Ability to work in a fast-paced environment, manage multiple projects, demonstrate consistent productivity, and meet project timelines
  • Ability to work independently and collaboratively
  • Remote location (work from home office) is possible

Salary and Benefits:

Seventh Wave offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance. 

For more information please contact Dr. Stewart Jacobson, Vice President of Pathology Services at

Merck Sharpe & Dohme Corp, West Point, PA—Principal Scientist

Company: Merck Sharpe & Dohme Corp
Location: West Point, PA
Job Title: Principal Scientist

Please visit the link to review the complete job description and to apply online.

Our Company is a leading global biopharmaceutical company with a 125-year history of Inventing for Life with an inspiring mission to make discoveries that positively impact global healthcare. Our success is driven by putting patients first, operating with the highest integrity, and committing fully to our vision to make a difference in the lives of people globally. With our diverse pipeline of vaccines, biologics, small molecules, and newer modalities, we are at the forefront of research to advance the prevention and treatment of diseases such as cancer, cardiometabolic diseases, Alzheimer’s disease and infectious diseases including HIV and Ebola.

About Us:

Our Company’s Research and Development (R&D) Laboratories’ nonclinical safety assessment group at the West Point, Pennsylvania site is seeking an anatomic pathologist to join a highly collaborative team of scientists (14 anatomic pathologists, 2 clinical pathologists, and over 30 exceptional technical staff), working at a GLP-compliant facility with state-of-the-art anatomic, molecular and clinical pathology laboratories.

Our Company’s pathologists are integral members and leaders of collaborative cross functional scientific teams, addressing challenges from early discovery to late development. Our Company’s pathologists provide scientific leadership in the design and conduct of postmortem evaluation of studies and integrate the interpretation of postmortem data into the safety profile of drug candidates. 

Some of the key responsibilities for this scientific role include:

Employ both routine H&E evaluations as well as other specialized techniques to characterize the safety profile of new drugs from toxicology and investigative studies

Work independently to analyze data, interpret and determine the significance of results for postmortem evaluations, review literature and design experiments to help teams solve scientific problems

Serve as Program Pathologist, providing scientific input and oversight across studies from very early discovery to late stage development, following molecules throughout their lifetime

Communicate with study team/drug development teams on study findings and participate on cross-functional teams to elucidate mechanisms of toxicity, utilizing additional tools and applications that are all available on-site, including:

  • An industry-leading suite of on-site in vitro and in vivo assay capabilities
  • Transmission electron microscopy
  • Immunohistochemistry and in situ hybridization
  • Quantitative digital image analysis and targeted machine learning applications
  • In vivo imaging tools (e.g., magnetic resonance imaging)

Develop novel biomarkers and predictive models to de-risk drug candidates for safety-related liabilities

Our Company’s pathologists also serve as nonclinical safety assessment leads on drug development teams, overseeing the design and execution of studies, and generation of regulatory strategy and communications with global regulatory agencies to support the development of drug candidates

About You:

  • Doctor of Veterinary Medicine (DVM)
  • Residency in anatomic / toxicologic pathology
  • ACVP-board certification in anatomic pathology
  • PhD in Toxicology, Pathology, or related discipline
  • 2–5 years of experience as a pathologist in biotech, pharma or at a CRO is a plus, but not required

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.




If you need an accommodation for the application process, please email us at

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster
EEOC GINA Supplement​
OFCCP EEO Supplement

OFCCP Pay Transparency Rule


We are an equal opportunity employer, Minority/Female/Disability/Veteran - proudly embracing diversity in all of its manifestations.

Citoxlab - A Charles River Company, Laval, QC, Canada—Veterinary Anatomic Pathologist

Company: Citoxlab - A Charles River Company
Location: Laval, QC, Canada
Job Title: Veterinary Anatomic Pathologist


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guides us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe.

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe.

Our Canadian facility, located in Laval (Montreal area), is looking for a Veterinary Anatomic Pathologist.

Key Duties
We are looking for highly motivated candidates with experience in toxicologic or investigative pathology in a Contract Research Organization or pharmaceutical industry;
This position report to the Director of Pathology with extensive interaction with the company’s scientific and technical staff.


  • Provide scientific expertise in pathology according to sponsors requirements;
  • Provide scientific and technical expertise in immunohistochemistry techniques and associated molecular pathology applications;
  • Supervise necropsies and perform histopathological examinations on a wide variety of laboratory species;
  • Write pathology reports in support of the toxicology program;
  • Perform pathology peer reviews;
  • Review clinical pathology data.

Knowledge, skills and abilities

  • A minimum of 1 to 3 years’ experience in nonclinical drug development in a contract research environment;
  • Strong knowledge of related legislation, principles, practices and procedures;
  • High degree of self-motivation with effective organizational and time management skills;
  • Collaborative and team building skills;
  • Fluent in spoken and written English required, French would be an asset;
  • Computer knowledge including Microsoft Office.


  • Doctorate in Veterinary Medicine or equivalent, and formal Residency training in Veterinary Pathology;
  • Board certification by the American College of Veterinary Pathologists (ACVP) or European College of Veterinary Pathologists (ECVP);
  • PhD is a definite asset;
  • Prior experience in a CRO or in a comparable drug development environment (e.g. pharmaceutical or biotechnology company) and a strong interest in life sciences will be highly valued.

Additional information
We offer:

  • Flexible work schedule;
  • Coaching/mentoring;
  • Competitive compensation plan;
  • Flexible social benefits program;
  • Group RRSP to which the employer contributes.

If you are interested in hearing more about this opportunity or would like to apply for this position, please contact

Novartis Institutes for BioMedical Research, Inc., Cambridge, MA—Pathologist, NIBR Oncology Translational Research

Company: Novartis Institutes for BioMedical Research, Inc.
Location: Cambridge, MA
Job Title: Pathologist, NIBR Oncology Translational Research

The Oncology Translational Research group at NIBR is recruiting a research-oriented pathologist to provide scientific and clinical expertise to inform patient selection strategies and biomarker development. You will partner across the full range of Oncology programs (small molecule, biotherapeutics and Immuno-Oncology) from target identification through First-in-Human studies.


  • Provide strategic scientific and clinical input to the Oncology Pathology & Biomarkers group and project teams locally and internationally
  • Work closely with research and early clinical project teams (Scientists and Physician-Scientists) to design and interpret slide and human tissue-based experiments; evaluate biomarkers in human and xenograft samples via techniques such as IHC, ISH, IF, LCM, and protein assays
  • Explore utility of innovative tissue-based technologies for drug discovery (e.g. deep learning on digital pathology images, mass cytometry imaging, spatial transcriptomics)
  • Lead scientific associates to design and conduct experiments, to interpret and challenge experimental results
  • Network internally and externally with other pathologists, clinicians and scientists on project activities
  • Engage in independent research with colleagues across Oncology Translational Research and broader Novartis Institutes for BioMedical Research Disease Areas and Translational Medicine groups
  • Author internal reports and presentations
  • Champion writings of external publications and patent applications
  • Conduct and supervise your lab to ensure compliance with HSE guidelines and policies

Desirable Requirements:

  • Candidates must have an MD, MD/PhD, or DVM/PhD with formal training in anatomic pathology. Hematopathology fellowship or experience characterizing immune infiltrates preferred.
  • Demonstrated expertise in tissue-based analysis, such as interpretation of IHC, interpretation of tissue microarrays, and image analysis.
  • Working knowledge of DNA/RNA based methodologies for tissue-based analysis preferred.
  • Demonstrated success in supervising technical staff.
  • PhD-level research experience in pathology, molecular genetics, immunology or related field preferred.
  • Excellent communication skills (written and oral).
  • The ideal candidate will be collaborative, innovative, and self-directed, with outstanding teamwork capabilities.

Why consider Novartis?

750 million.

That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Please visit the link to review the complete job description and to apply online.

Alnylam Pharmaceuticals Inc., Cambridge, MA—Program Toxicologic Pathologist

Company: Alnylam Pharmaceuticals Inc.
Location: Cambridge, MA
Job Title: Program Toxicologic Pathologist


Alnylam was founded in 2002 on a revolutionary vision and bold mission which remain firmly in place today. We are leading the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to transform the lives of people with rare genetic, cardio-metabolic, hepatic infectious, and central nervous system diseases with unmet need. Our first medicine, the first-ever RNAi therapeutic, has recently been approved by the FDA in the US for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults and by the European Medicines Agency in the EU for the treatment of hATTR amyloidosis in adults with stage 1 or stage 2 polyneuropathy. In addition, Alnylam has four investigational medicines in late-stage development. Alnylam is proud to have been recognized as one of The Boston Globe’s Top Places to Work in 2015, 2016, 2017 and 2018- four years in a row!

Alnylam has a full-time opening for a Toxicologic Pathologist with demonstrated expertise in drug development. The company’s pipeline has recently expanded beyond traditional liver indications to include both CNS and Ocular indications. Therefore, a successful candidate must be able to provide expert pathology support, scientific leadership and play an active role in the process of drug development from early-stage research through marketed products across several therapeutic areas/indications. In this position, you will play a pivotal role across a broad range of existing and emerging projects through the design, implementation and data analysis for both investigative and research studies. Qualified individuals will also participate in pathology oversight for regulatory toxicology studies, including the evaluation clinical pathology data, primary histopathology evaluations for in-house studies, and pathology peer review for GLP studies conducted at CROs. The successful candidate will have an opportunity to participate on drug development teams, overseeing the design and execution of studies, and generation of regulatory strategy and communications with global regulatory agencies to support development of drug development candidates.

Summary of Key Responsibilities:

  • Conduct gross and microscopic examination of animal tissues from toxicology and investigative studies, interpret and determine the significance of results for clinical pathology, organ weight, necropsy and histopathology data
  • Provide concise written pathology reports that accurately and completely reflect the data collected and the impact on drug development, drug registration and human safety
  • Represent the Early Development group on early program teams supporting research and development projects
  • Conduct pathology peer reviews of GLP studies at CROs
  • Assist in the regulatory toxicology strategy, guiding development and project prioritization by responding quickly to data from ongoing studies and providing input to management and development teams
  • Summarize experimental results for presentations both within and outside of the company


  • Doctor of Veterinary Medicine (DVM)
  • Residency or other specialty training in anatomic / toxicologic pathology
  • ACVP-board certification in anatomic pathology
  • 3-5 years of experience as a pathologist in biotech, pharma or at a CRO
  • Experience working in a GLP-compliant environment
  • PhD in Toxicology or Pathology, or another relevant field of expertise, is strongly preferred
  • Level commensurate with training and experience level of the individual.

Alnylam Pharmaceuticals is an EEO employer committed to an exciting, diverse, and enriching work environment.

Please visit the link to review the complete job description and to apply online.

Charles River Laboratories, Multiple Listings—Veterinary Pathologist

Company: Charles River Laboratories
Location: Multiple Listings
Job Title: Veterinary Pathologist

We currently have openings for a Veterinary Pathologist II and a Senior Veterinary Pathologist in locations in Canada and across the United States.


  • Perform macroscopic and microscopic tissue evaluation and interpretation of assigned studies.
  • Record pathology findings in data capturing system(s).
  • Prepare complex reports delineating pathological findings and detailing all test article effects
  • Interact with clients to assure satisfaction and to market services.
  • May assist with necropsy supervision and may conduct necropsies, including gross pathology interpretation, sample collection and fixation.
  • As needed, work with study directors to ensure data is accurately integrated into study reports.
  • Provide training, technical guidance and leadership to laboratory staff and to less experienced pathologists, as needed.
  • Provide advanced scientific expertise for experimental design and other aspects of research studies as needed.
  • Perform all other related duties as assigned.


  • Education: Doctoral degree (D.V.M./V.M.D.) from an accredited veterinary school, or acceptable international equivalent in veterinary medicine.
  • Certification/Licensure: American or European College of Veterinary Pathologists (A.C.V.P; E.C.V .P) board-certification required.
  • Experience: 1 or more years of pathology experience post ACVP/ECVP certification; specialized training and/or experience in toxicology pathology preferred.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Other: Able to work on complex problems in which analysis of situations or data requires an in-depth evaluation of various factors. Has demonstrated success in technical proficiency, scientific creativity, collaboration with others and independent thought; has a reputation as an emerging leader with sustained performance and accomplishment.
  • Computer literacy in word processing, spreadsheet and database software
  • Working knowledge of French preferred

For this position, we have locations in Canada and all over the United States.

For our Veterinary Pathologist II positions, please apply to the following locations:

For our Senior Veterinary Pathologist positions, please apply to the following locations:

West Tennessee Regional Forensic Center, Memphis, TN—Chief Medical Examiner

Company: West Tennessee Regional Forensic Center
Location: Memphis, TN
Job Title: Chief Medical Examiner

The WTRFC performs approximately 1,000 autopsies per year for 13 counties west of the Tennessee River. The center encounters a wide variety of cases, including traumatic deaths, toxicological deaths, and natural deaths. The Chief Medical Examiner will perform death investigations, establish cause and manner of death, formulate conclusions, opinions or testimony in judicial proceedings, and to be available for consultations as necessary.

Duties and Responsibilities:

  • Responsible for directing the overall operation of the West Tennessee Regional Forensic Center by performing highly responsible and complex administrative work in planning, coordinating, directing, implementing and controlling the statutory functions as defined by the Tennessee Post-Mortem Examination Act; and to do related work as required
  • Provide direct or indirect services to District Attorneys, the Courts, the Attorney General, funeral homes, families of decedents, hospitals and major medical academic centers, insurance companies, organ procurement organizations, local and state police investigators, fire departments, a variety of state agencies, and various Federal programs and agencies.
  • Coordinate activities of the West Tennessee Regional Forensic Center with the Shelby County Department of Health.
  • Responsible for directing the overall operation of the Medical Examiner's Office which carries out medicolegal death investigations for the County, and provides autopsy services for up to 15 other counties in the north, central and eastern portions of the state.
  • Perform the responsibilities of a forensic pathologist (i.e. doing autopsies) and responsible for reviewing the forensic pathology functions done in the setting.
  • Counsels’ families in person or thru the telephone on increasing their level of understanding regarding the cause and manner of the death of the person involved as well as the psychological and physiologic aspects of the case.
  • In certain circumstances, the Chief Medical Examiner may be obligated to be a witness in the courts of law to aid in investigation of cases.


  • Education: Graduation from an accredited medical school and board certification in Forensic Pathology by the American Board of Pathology
  • Experience: Minimum of 8-10 years of experience in a responsible position involving practice in the field of Forensic Pathology, prior management experience is required. OR, any combination of education and experience that shall be substantially equivalent to the above education and experience
  • License/Certification: Must possess licensure to practice medicine and certification by the American Board of Pathology in the field of Anatomic Pathology and Forensic Pathology at the time of appointment and must maintain such licensure and certification as a condition of employment.
Please visit the link to review the complete job description and to apply online.

Vertex Pharmaceuticals Inc., Boston, MA—Director, Investigative Toxicologic Pathologist

Company: Vertex Pharmaceuticals Inc.
Location: Boston, MA
Job Title: Director, Investigative Toxicologic Pathologist

Preclinical Safety Assessment (PSA) is a global function responsible for the design and conduct of comprehensive nonclinical safety programs for the evaluation of Vertex therapies at all stages of discovery and development. Vertex Pharmaceuticals uses cutting edge science and technology to perform robust assessments of novel therapies for the treatment of the most serious diseases with unmet medical need. Our culture enables individual empowerment where ‘We Wins, Fearless Pursuit of Excellence, and Innovation’ are more than just corporate values; they are part of our everyday lives. PSA pathologists have significant roles in the drug development process beginning in early discovery and continuing through the entire drug development value chain resulting in successful registration and marketing approval.

Key Responsibilities:

  • Strategic and scientific leadership in the design, conduct and interpretation of pathology endpoints for animal model development, target identification/validation, and in vivo pharmacology and nonclinical biomarker development studies including the use of cutting-edge molecular diagnostic and digital imaging technologies as part of a newly created discovery & investigative pathology group
  • Anatomic pathology evaluation of investigative pathology and regulatory toxicity studies from lead identification/optimization through registration and post-marketing including peer review of outsourced nonGLP and GLP toxicology studies
  • Expert scientific leadership in discovery, translational research, and regulatory nonclinical safety profiling activities as a key partner on cross-functional teams within Vertex, working with a high-functioning multidisciplinary team of preclinical safety and biomarker scientists including a Board-certified veterinary clinical pathologist and an extensive network of external consultants and contract research organizations
  • Participation in regulatory submission document preparation, poster presentations and scientific publications, including addressing queries from global health authorities

The position includes opportunities for potential additional roles including:

  • Preclinical safety representative on discovery and/or development project teams
  • Nonclinical safety evaluation of in-licensing opportunities supporting business development

Minimum Qualifications:

  • DVM or equivalent and ACVP/ECVP board certification in veterinary anatomic pathology.
  • PhD in a relevant scientific discipline is strongly preferred
  • 3+ years of work experience in Discovery and/or Toxicologic pathology in the pharmaceutical/biotechnology sector including the conduct of GLP peer reviews
  • Extensive practical experience using imaging technologies and molecular diagnostic pathology techniques to understand the pathologic basis of disease and support drug discovery and development
  • Demonstrated excellence in oral and written communications, critical thinking and issue resolution skills, and scientific collaboration, guidance, and mentoring of non-DVM scientists and laboratory associates

Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases.

Please visit the link to review the complete job description and to apply online.

Regeneron Pharmaceuticals, Tarrytown, NY—Senior Research Pathologist/ Fellow, Pathology

Company: Regeneron Pharmaceuticals
Location: Tarrytown, NY
Job Title: Senior Research Pathologist/ Fellow, Pathology

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.


DVM, PhD, board certified (DACVP) Anatomic Pathologist with solid experience assessing tissues from investigative pathology and regulatory toxicology studies. The selected individual will have primary responsibility for pathology peer review of regulatory studies conducted at CROs. Using the standard tools of histopathology and immunohistochemistry (IHC) and the more novel tools of RNA/Scope, the pathologist will also be expected to furnish pathology support for Discovery efforts in a variety of therapeutic focus areas (TFAs) including: Inflammation/Immune Diseases, Neuroscience/Pain, Oncology/Angiogenesis, Infectious Diseases, Ophthalmology, Obesity/Metabolic Diseases, Skeletal, Muscle and Genetic Diseases, as well as Cardiovascular/Renal/Fibrosis. In addition, the successful individual will provide leadership in the utilization of the Aperio System and its suite of powerful viewing and analysis tools to support digital pathology productivity at Regeneron.


  • Reports to the Senior Director/ Head of Pathology.
  • Participates in strategy development in Drug Safety and Pharmacometrics (DSP) through advocacy for the Pathology components of regulatory/research studies
  • to help design, develop, and implement research programs to support facets of drug development in alignment with REGN’s varied initiatives.
  • Utilizes mastery level skills in anatomic, toxicologic and molecular pathology and strategic leadership to design and execute research and development projects within and outside own discipline. Is influential in developing project strategy — provides intellectual vision and guidance.
  • Provides expert histopathology, IHC and RNAScope evaluation support for the phenotypic characterization of REGNs animal disease and in vivo drug efficacy models
  • Performs GLP-compliant peer review of the pathology aspects of REGN toxicology studies at CROs
  • Provides expert translational pathology consultation to project teams to facilitate interpretation of preclinical data in the context of human diseases
  • Collaborates on teams to develop predictive and prognostic biomarkers in support of REGN pipeline drugs.
  • Collaborates with other Pathologists to develop a strong in-house digital pathology program
  • Makes a contribution to multidisciplinary meetings. Shares cross-functional skills and knowledge at a wide variety of meetings. Initiates and edits multi-contributor internal and/or external "publications" (i.e., Peer Reviewed publications, SOP’s, Patents, Business Plans, etc.). Prepares reports, presentations and manuscripts. Disseminates study findings to toxicologists, research investigators, project teams and others, including at national and international seminars as needed.


  • At least 2 (Senior Research Pathologist)/5 (Fellow, Pathology) years of toxicologic pathology experience that should ideally include drug discovery support.
  • Clear demonstration of high-quality scholarly productivity in investigative pathology or other areas of biomedical research evidenced by publications is desirable.
  • The ideal candidate must have demonstrated ability to handle regulatory as well as discovery projects and worked successfully in a variety of therapeutic projects teams.
  • Experience with large molecule projects will be an advantage.
  • The successful candidate will be familiar with, if not expert in molecular pathology and image analysis techniques and will have excellent verbal and written communication skills.
  • Minimal educational requirements: Ph.D./ DVM/ Board Certified DVM Pathologist

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Please visit the link to review the complete job description and to apply online.

Covance, Chantilly, VA—Veterinary Anatomic Pathologist

Company: Covance
Location: Chantilly, VA
Job Title: Veterinary Anatomic Pathologist

Covance is Hiring!

Are you passionate about advancing your career while making a difference in patient’s lives?

Are you looking for an exciting career with room for growth within a supportive team?

If you answered yes to these, we’d like you to consider joining Covance. We have Veterinary Anatomic Pathologist positions open at our following sites:

  • Chantilly, Virginia
  • Harrogate, United Kingdom
  • Münster, Germany

Come join a global team of veterinary pathologists focused on providing high quality support to nonclinical studies spanning all phases of drug development.

Covance’s work in developing new pharmaceutical solutions has an incredible impact on millions of lives worldwide. Be a part of this life-saving work.

If interested in learning more about these opportunities, please contact

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Takeda, Boston, MA—Associate Scientific Director, Pathology

Company: Takeda
Location: Boston, MA
Job Title: Associate Scientific Director, Pathology

As an Associate Scientific Director, Pathology you will be empowered to provide pathology and toxicology expertise and collaborate with Global Head of Pathology and Drug Safety Therapeutic Leaders. A typical day will include:


  • Provide pathology and toxicology expertise and represent DSRE on discovery, research and development project teams
  • Collaborate with Global Head of Pathology and Drug Safety Therapeutic Leaders in the development and execution of strategies for discovery and development programs
  • Provide stewardship, toxicology and/or pathology support and interpretation of toxicology studies on drug candidates with subsequent preparation and review of regulatory documents and support of Regulatory Affairs and Clinical groups for all phases of development, including IND through registration across all therapeutic indications
  • Develop talent and mentor junior toxicologists or pathologists (Global) and the Comparative Medicine in vivo toxicology group (Cambridge site only)
  • Scientific leader with deep subject-matter expertise, driving project team progression and development of technical capabilities


  • Evaluate histopathology specimens from a variety of nonclinical animal species used in nonclinical toxicity studies to determine target organs and morphologic toxicity profile of potential novel pharmaceutical agents.
  • Conduct peer reviews of pathology data generated off-site.
  • Provide histopathology support for peripheral experimental modalities used in other departments such as immunohistochemistry and xenograft tumor models.
  • Serve on project teams for drug discovery, transition and development teams
  • Design and interpret toxicology studies to address human safety concerns and relevance
  • Review study reports and regulatory documents for technical accuracy and regulatory adequacy
  • Prepare regulatory documents (BB, IND, IB, DSUR, BLA, MAA, NDA, JNDA) and respond to health authorities concerning toxicology issues
  • Collaborate and interface with project leaders across Takeda to ensure transition of programs into development
  • Develop strategies for addressing toxicology issues and present them to management and governance committees
  • Work with CMC to qualify impurities as needed
  • Work with Comparative Medicine in vivo toxicology group on issues regarding in vivo studies and the 3Rs
  • Participate in local and national toxicology/pathology meetings and represent Takeda at these meetings
  • Independently manages workload and expectations Scientifically
  • Independent Scientific driver for research strategy that impacts group internally and outside area of function

Education, Experience, Knowledge and Skills:

  • DVM and PhD degree in a scientific discipline with 10+ years experience, or MS with 14+ years experience, or BS with 16+ years experience
  • Pharmaceutical drug development experience including as a project team representative (5+)
  • Proficiency in histopathology
  • In-depth understanding of molecular biology
  • Excellent communication skills (written and oral)
  • Ability and desire to take on leadership roles
  • Ability to team with colleagues across different functional areas
  • Proficiency with computer systems such as word processing, spreadsheets and databases


  • Certification in veterinary pathology (ACVP, ECVP, or JCVP)
  • Certification in toxicology (ABT or equivalent) - optional

Physical Demands:

  • Routine demands of an office based environment.

Travel Requirements:

  • Willingness to travel to various meetings or client sites, including overnight trips. Some international travel may be required.

What Takeda Can Offer You:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs
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